Реакция #423247

Уравнение реакции

calcium phosphate

sodium alendronate

→

Alendronate

Растворители

water

Условия реакции

Обработка

1. 1
   Другоеwas prepared
2. 2
   ДругоеThe suspension was placed in a tube
3. 3
   Другоеthe most part of the supernatant was removed
4. 4
   ФильтрацияThe solid residue was filtered off
5. 5
   Промывкаwashed several times with small portions of ultrapure water
6. 6
   Другоеdried at room temperature

Методика

A suspension of calcium phosphate was prepared by introducing 100 mg of CDA into 8.75 ml of ultrapure water mixed with 1.25 ml of a 0.02 mol.l−1 sodium alendronate aqueous solution. The suspension was placed in a tube maintained at room temperature, and was stirred with a rotary stirrer at 16 rpm for 5 days. The suspension was then centrifuged and the most part of the supernatant was removed. The solid residue was filtered off, washed several times with small portions of ultrapure water, and then dried at room temperature. The resulting solid contained 7.4 wt % alendronate.

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