Реакция #41956

Уравнение реакции

Chloroacetaldehyde diethyl acetal

potassium benzoate

potassium bromide

DMF

→

compound

Выход 34.1%

2-benzoyloxyacetaldehyde Diethyl Acetal

Выход 34.1%

Растворители

ethyl acetate

water

Условия реакции

Обработка

1. 1
   Температураby refluxing
2. 2
   ФильтрацияAfter filtration
3. 3
   Промывкаthe organic layer was washed with water (30 mL)
4. 4
   Сушкаwas dried over anhydrous sodium sulfate
5. 5
   ФильтрацияSubsequent filtration and vacuum concentration

Методика

Chloroacetaldehyde diethyl acetal (2.00 g), potassium benzoate (1.91 g), potassium bromide (0.30 g) and DMF (20 mL) were placed in a three-neck flask, followed by refluxing. Twenty hours later, the reaction mixture was cooled to room temperature, and water (30 mL) and ethyl acetate (80 mL) were added thereto, followed by stirring. After filtration, the organic layer was washed with water (30 mL) and was dried over anhydrous sodium sulfate. Subsequent filtration and vacuum concentration yielded the target compound (0.97 g) in a yield of 31%.

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