Реакция #417926

Уравнение реакции

sodium hydroxide

33

methyl 4-(undec-4Z-enyloxy)benzoate

→

white solid

Выход 98.1%

4-(undec-4Z-enyloxy)benzoic acid

Выход 98.1%

Растворители

methanol

Условия реакции

Обработка

1. 1
   ТемператураThe solution is refluxed for 20 hours
2. 2
   ДругоеAfter evaporating off the solvent
3. 3
   Экстракцияextracted with DCM

Методика

550 μL of 1 N sodium hydroxide solution (550 μmol) are added portionwise to 109 mg of 33 (358 μmol) in methanol (4 mL). The solution is refluxed for 20 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 102 mg of a white solid are obtained, i.e. a yield of 98%.

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