Реакция #417924

Уравнение реакции

sodium hydroxide

29

methyl 2-(undec-4Z-enyloxy)benzoate

→

yellow oil

Выход 99.5%

2-(undec-4Z-enyloxy)benzoic acid

Выход 99.5%

Растворители

methanol

Условия реакции

Обработка

1. 1
   ТемператураThe solution is refluxed for 24 hours
2. 2
   ДругоеAfter evaporating off the solvent
3. 3
   Экстракцияextracted with DCM

Методика

500 μL of 1 N sodium hydroxide solution (500 μmol) are added portionwise to 80 mg of 29 (263 μmol) in methanol (3 mL). The solution is refluxed for 24 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 76 mg of a yellow oil are obtained, i.e. a yield of 99%.

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