Реакция #417901

Уравнение реакции

phosphoryl chloride

dibenzo[f,h]quinoxaline-1-oxide

potassium carbonate

→

2-Chloro-Dibenzo[f,h]Quinoxaline

Выход 93.0%

Растворители

water

Условия реакции

Обработка

1. 1
   Другоеobtained in the above Step 1
2. 2
   Температураwhile being heated
3. 3
   Температураunder reflux for 1 hour
4. 4
   ФильтрацияThis solution was filtered
5. 5
   Промывкаthe obtained residue was washed with water
6. 6
   Другоеmethanol to give
7. 7
   Другоеthe object of the synthesis (as a pale yellow powder in a yield of 93%)
8. 8
   ДругоеThe synthesis scheme of Step 2

Методика

Next, 18 mL of phosphoryl chloride was dripped into 2.91 g of dibenzo[f,h]quinoxaline-1-oxide obtained in the above Step 1. This mixed solution was stirred while being heated under reflux for 1 hour. This mixed solution was poured into iced water, followed by addition of potassium carbonate so that the mixture was alkaline. This solution was filtered, and the obtained residue was washed with water and then methanol to give the object of the synthesis (as a pale yellow powder in a yield of 93%). The synthesis scheme of Step 2 is illustrated in the following (a″′-2-2).

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