Реакция #40806

ord-096060c9f0dd4d369daa7a6032a8f907

Уравнение реакции

CCCc1ccc(-c2ccc(C(=O)OCC)nc2-c2ccccc2)cc1
ethyl 6-phenyl-5-(4-propylphenyl)-pyridine-2-carboxylate
CCCc1ccc(-c2ccc(C(=O)OCC)nc2-c2ccccc2)cc1
Compound 24
CCCc1ccc(-c2ccc(C(=O)OCC)nc2-c2ccccc2)cc1
ethyl 6-phenyl-5-(4-propylphenyl)-pyridine-2-carboxylate
→
CCCc1ccc(-c2ccc(C(=O)OC)nc2-c2ccccc2)cc1
title compound
CCCc1ccc(-c2ccc(C(=O)OC)nc2-c2ccccc2)cc1
Methyl 6-Phenyl-5-(4-propylphenyl)-pyridine-2-carboxylate

Реактанты

CCCc1ccc(-c2ccc(C(=O)OCC)nc2-c2ccccc2)cc1
ethyl 6-phenyl-5-(4-propylphenyl)-pyridine-2-carboxylate
CCCc1ccc(-c2ccc(C(=O)OCC)nc2-c2ccccc2)cc1
Compound 24
CCCc1ccc(-c2ccc(C(=O)OCC)nc2-c2ccccc2)cc1
ethyl 6-phenyl-5-(4-propylphenyl)-pyridine-2-carboxylate

Реагенты

O=S(=O)(O)O
H2SO4

Растворители

CO
MeOH

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    Другоеwere reacted

Методика

Following General Procedure E, ethyl 6-phenyl-5-(4-propylphenyl)-pyridine-2-carboxylate (Compound 24, 67 mg, 0.19 mmol) and conc. H2SO4 (3 drops) in MeOH (3 ml) were reacted to produce the title compound as a white solid.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07728014B2uspto-grants-2010_06