Реакция #4071

Уравнение реакции

methyl α-(2-methylphenyl)-β-methoxyacrylate

N-bromosuccinimide

succinimide

→

colorless crystals

Выход 97.3%

Methyl α-(2-bromomethylphenyl)-β-methoxyacrylate

Выход 97.3%

Растворители

CCl4

Условия реакции

Обработка

1. 1
   ФильтрацияThe mixture is filtered
2. 2
   Другоеthe filtrate is evaporated down
3. 3
   workup.DISSOLUTIONthe oil which remains is dissolved in about 5 ml of acetone
4. 4
   Другоеbrought to crystallization with n-hexane

Методика

20.6 g of the methyl α-(2-methylphenyl)-β-methoxyacrylate obtained as described in method A, 17.65 g of N-bromosuccinimide, 0.2 g of azobisisobutyronitrile and 150 ml of CCl4 are slowly heated to 90° C. and kept at this temperature until all of the succinimide floats on the solvent. The mixture is filtered, the filtrate is evaporated down, and the oil which remains is dissolved in about 5 ml of acetone and brought to crystallization with n-hexane. 27.5 g of colorless crystals of melting point 86°-87° C. are obtained.

Источник