Реакция #40695

Уравнение реакции

compound

benzyl 2-(3-methylphenoxy)-1-[(2-nitroanilino)methyl]ethylcarbamate

hydrobromide acetic acid

→

title compound

3-(3-methylphenoxy)-N1-(2-nitrophenyl)-1,2-propanediamine hydrobromide

Растворители

dichloromethane

dichloromethane

Условия реакции

Обработка

1. 1
   Промывкаwashed with saturated aqueous sodium hydrogen carbonate
2. 2
   СушкаThe organic layer was dried over anhydrous sodium sulfate
3. 3
   Другоеthe solvent was evaporated

Методика

To the compound obtained in Step 2 were added 30% hydrobromide/acetic acid (1 ml) and dichloromethane (2 ml), and the mixture was stirred at 0° C. for 2 hrs. The mixture was diluted with dichloromethane, and washed with saturated aqueous sodium hydrogen carbonate. The organic layer was dried over anhydrous sodium sulfate and the solvent was evaporated to give the title compound as a crude product.

Источник