Реакция #4069

Уравнение реакции

N-bromosuccinimide

methyl phenylacetate

→

title compound

Выход 93.1%

Methyl Bromo-Phenylacetate

Выход 93.1%

Растворители

carbon tetrachloride

Условия реакции

Обработка

1. 1
   Температураto reflux
2. 2
   Температураrefluxed for about 12 hours
3. 3
   Фильтрацияfiltered
4. 4
   КонцентрированиеThe filtrate was concentrated by evaporation under vacuum

Методика

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

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