Реакция #4031

Уравнение реакции

Methyl perfluorobutyrate

sodium trimethylsilanolate

→

sodium perfluorobutyrate

Выход 84.0%

Растворители

ether

Условия реакции

Обработка

1. 1
   ФильтрацияThe solid was filtered under nitrogen
2. 2
   Промывкаwashed with dry ether
3. 3
   Другоеdried under a stream of nitrogen

Методика

Methyl perfluorobutyrate (12.81 g, 56 mmol) was added dropwise to a stirred solution of sodium trimethylsilanolate (6.3 g, 56 mmol) in dry ether (300 mL) at room temperature under nitrogen. The reaction mixture was stirred overnight. The solid was filtered under nitrogen, washed with dry ether, and dried under a stream of nitrogen to afford sodium perfluorobutyrate (11.1 g, 84% yield) as a white solid: 19F NMR (D2O) δ -79.6 (t, J=8 Hz, CF3 --, 3F), -117.2 (q, J=8 Hz, CF3CF2CF2 --, 2F), -126.2 ppm (s, CF3CF2 --, 2F). Anal. Calcd. for C4F7NaO2 : C, 20.36; F, 56.35; Na, 9.74. Found: C, 20.84, 20.61, 20.58; F, 56.68, 53.24; Na, 9.89, 9.65.

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