Реакция #3975

ord-07ba6e5f908b4ae49ca949e471af2338

Уравнение реакции

COc1ncc2[nH]c(-c3cc(S(=O)(=O)Cl)c(Cl)cc3OC)nc2n1
2-methoxy-8-(2-methoxy-4-chloro-5-chlorosulfonyl-phenyl)-purine
CN
methylamine
→
CNS(=O)(=O)c1cc(-c2nc3nc(OC)ncc3[nH]2)c(OC)cc1Cl
2-Methoxy-8-(2-methoxy-4-chloro-5-methylaminosulfonyl-phenyl)-purine

Реактанты

COc1ncc2[nH]c(-c3cc(S(=O)(=O)Cl)c(Cl)cc3OC)nc2n1
2-methoxy-8-(2-methoxy-4-chloro-5-chlorosulfonyl-phenyl)-purine
CN
methylamine

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Prepared analogously to Example 11 from 2-methoxy-8-(2-methoxy-4-chloro-5-chlorosulfonyl-phenyl)-purine and aqueous methylamine solution.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US04722929uspto-grants-1988_02