Реакция #3942

Уравнение реакции

n-hexyl isocyanate

3-[4-(4-chlorobenzyl)homopiperazin-1-yl]propanethiol

→

N-(n-hexyl)-S-{3-[4-(4-chlorobenzyl)homopiperazin-1-yl]propyl}thiocarbamate dihydrochloride

Выход 77.6%

Растворители

methylene chloride

Условия реакции

Методика

The procedure described in Example 2 was followed, using 1.3 g of n-hexyl isocyanate, 3.0 g of 3-[4-(4-chlorobenzyl)homopiperazin-1-yl]propanethiol and 75 ml of methylene chloride, to give 1.3 g (33% of theory) of N-(n-hexyl)-S-{3-[4-(4-chlorobenzyl)homopiperazin-1-yl]propyl}thiocarbamate dihydrochloride as a tan powder, M.p. 183°-187° C.

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