Реакция #3708

Уравнение реакции

3-methoxy-4-nitrobenzoic acid

thionyl chloride

→

3-Methoxy-4-nitrobenzoyl chloride

Растворители

iso-octane

Условия реакции

Обработка

1. 1
   Температураis heated
2. 2
   Температураto reflux for 2 hours
3. 3
   Другоеthe mixture evaporated in vacuo to a solid residue
4. 4
   ПромывкаThe residue is washed with iso-octane (2×2 ml)
5. 5
   Другоеdried in vacuo
6. 6
   Другоеto give 1.08 g of cream

Методика

A stirred suspension of 1.0 g of 3-methoxy-4-nitrobenzoic acid and 1.40 ml of thionyl chloride is heated to reflux for 2 hours. The mixture is cooled to room temperature, 2 ml of iso-octane added and the mixture evaporated in vacuo to a solid residue. The residue is washed with iso-octane (2×2 ml), dried in vacuo to give 1.08 g of cream colored solid.

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