Реакция #363851

ord-7ca2834667e041faa17650f1c4aef4b1

Уравнение реакции

Cc1cc([N+](=O)[O-])ccc1N=C=S
2-Methyl-4-nitrophenyl isothiocyanate
CC(C)CN
isobutylamine
CC(Cl)C(=O)O
α-chloropropionic acid
→
Cc1cc([N+](=O)[O-])ccc1N=C1SC(C)C(=O)N1CC(C)C
2-(2-methyl-4-nitrophenylimino)-3-isobutyl-5-methyl-1,3-thiazolidin4-one

Реактанты

Cc1cc([N+](=O)[O-])ccc1N=C=S
2-Methyl-4-nitrophenyl isothiocyanate
CC(C)CN
isobutylamine
CC(Cl)C(=O)O
α-chloropropionic acid

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

2-Methyl-4-nitrophenyl isothiocyanate was reacted with isobutylamine followed by α-chloropropionic acid according to Method C8a to afford 2-(2-methyl-4-nitrophenylimino)-3-isobutyl-5-methyl-1,3-thiazolidin4-one.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US06353006B1uspto-grants-2002_03