Реакция #351532

ord-2fd0cb85959e4ba889eb5e6891fecc2f

Уравнение реакции

COC(=O)c1cc(O)ccc1O
methyl 2,5-dihydroxybenzoate
Cc1ccc(S(=O)(=O)OCCC(C)CC(C)(C)C)cc1
3,5,5-trimethylhexyl p-toluenesulfonate
COC(=O)c1cc(OCCC(C)CC(C)(C)C)ccc1O
methyl 5-(3,5,5-trimethylhexyloxy)-2-hydroxybenzoate
Выход 76.0%

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Обработка

  1. 1
    ДругоеSynthesis

Методика

Synthesis was carried out in the same manner as in Example 1, except for replacing methyl 2,4-dihydroxybenzoate with methyl 2,5-dihydroxybenzoate and replacing 2-ethylhexyl bromide with 3,5,5-trimethylhexyl p-toluenesulfonate, to obtain methyl 5-(3,5,5-trimethylhexyloxy)-2-hydroxybenzoate represented by the following chemical formula (hereinafter referred to as compound 10) as a colorless, clear and oily substance in a yield of 76%. The analytical results are shown below. ##STR31##

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US05646184uspto-grants-1997_07