Реакция #350346

Уравнение реакции

2-octanone

calcium oxide

tetramethyl ammonium hydroxide

propionitrile

→

2,3-Dimethyl-2-Nonene Nitrile

Растворители

water

Условия реакции

Обработка

1. 1
   Другоеflask, equipped with a magnetic stirrer

Методика

Into a 100 ml. flask, equipped with a magnetic stirrer, thermometer, condensor, and static nitrogen head, was placed 13.6 g. of 2-octanone, 11 g. of propionitrile, 61 g. of calcium oxide and 0.3 g. of 25% tetramethyl ammonium hydroxide in water. The mixture was held at reflux (103° C.) for 16 hours at which time gas chromatographic analysis showed 7% product nitrile relative to starting ketone.

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