Реакция #349004

Уравнение реакции

o-Chlorobenzaldehyde

3-chloro-2-methyl aniline

→

N-(o-Chlorobenzylidene)-2-methyl-3-chloroaniline

Растворители

ethanol

Условия реакции

Обработка

1. 1
   workup.STIRRINGthe reaction mixture is stirred vigorously for an additional 5 mins
2. 2
   workup.WAITThe reaction mixture is left
3. 3
   workup.WAITstanding at room temperature for 10 mins
4. 4
   workup.WAIT, then it is placed in an ice bath for 0.5 hr
5. 5
   ДругоеThe crystals which formed
6. 6
   Другоеare collected
7. 7
   Промывкаwashed with 95% ethanol, and air
8. 8
   Другоеdried
9. 9
   ДругоеRecrystallization from 85% ethanol

Методика

o-Chlorobenzaldehyde (0.20 mole) is treated with 3-chloro-2-methyl aniline (0.20 mole) with vigorous stirring in a 1 l. Erlenmeyer Flask. After 15 mins., 33 cc of 95% ethanol is added and the reaction mixture is stirred vigorously for an additional 5 mins. The reaction mixture is left standing at room temperature for 10 mins., then it is placed in an ice bath for 0.5 hr. The crystals which formed are collected, washed with 95% ethanol, and air dried. Recrystallization from 85% ethanol gives N-(o-Chlorobenzylidene)-2-methyl-3-chloroaniline. m.p. 83°-85° C.

Источник