Реакция #329433

Уравнение реакции

compound

4-Chloro-6-hydrazinopyrimidine

4-pyrrolidin-1-ylpyridine

→

4-Hydrazino-6-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrimidine

Растворители

water

Условия реакции

Обработка

1. 1
   ДругоеThe solid which has precipitated out
2. 2
   Фильтрацияis filtered off
3. 3
   Промывкаwashed first with ethanol
4. 4
   Сушкаwith diethyl ether and dried in vacuo

Методика

A mixture of 2.0 g (13.8 mmol) of the compound from Example 7A and 4.3 g (27.7 mmol) 4-pyrrolidin-1-ylpyridine is stirred in 20 ml water at 100° C. for 16 h. The solid which has precipitated out is filtered off, washed first with ethanol and then with diethyl ether and dried in vacuo.

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