Реакция #319823

Уравнение реакции

2,6-dichlorotoluene

nitric acid

→

2,6-dichloro-3-nitrotoluene

Условия реакции

Обработка

1. 1
   Экстракцияextracted with diethyl ether
2. 2
   Промывкаthe extract is washed with an aqueous sodium hydrogen carbonate solution
3. 3
   Другоеdried
4. 4
   workup.DISTILLATIONThe solvent is distilled off under reduced pressure

Методика

To 2,6-dichlorotoluene (200 g) is added dropwise fuming nitric acid (d=1.52, 206 ml) at 25° to 30° C. After stirring for 30 minutes at room temperature, the mixture is poured into ice-water, extracted with diethyl ether, and the extract is washed with an aqueous sodium hydrogen carbonate solution and then dried. The solvent is distilled off under reduced pressure to give 2,6-dichloro-3-nitrotoluene as yellow crystals (253.2 g).

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