Реакция #318379

Уравнение реакции

( b )

2,2-bis(3,4,5-trimethoxyphenylmethyl)-1,3-dithiane

methanol

iodomethane

→

1,3-bis(3,4,5-trimethoxyphenyl)acetone

Условия реакции

Обработка

1. 1
   Температураwas maintained at 40° C
2. 2
   ДругоеThe solvent was then evaporated
3. 3
   Другоеto give an oily residue which
4. 4
   Другоеwas crystallized from a mixture of ethyl acetate and petroleum ether
5. 5
   Другоеto yield a solid

Методика

A solution of 72 g of the compound prepared in (b) above in 96% aqueous methanol was heated to 40° C., after which time 50 ml of iodomethane was added. The reaction mixture was then stirred for 24 hours, while the temperature was maintained at 40° C. The solvent was then evaporated to give an oily residue which was crystallized from a mixture of ethyl acetate and petroleum ether to yield a solid.

Источник