Реакция #318020

ord-c011e72e892c47f798ecff7a58a03f7a

Уравнение реакции

Cc1c(N)cccc1Cl
2-methyl-3-chloroaniline
NC(=O)c1cnc2ccc(I)cc2c1Cl
Intermediate 13
NC(=O)c1cnc2ccc(I)cc2c1Cl
4-Chloro-6-iodo-3-quinolinecarboxamide
→
Cc1c(Cl)ccc2c(Cl)c(C(N)=O)cnc12
Intermediate 68
Cc1c(Cl)ccc2c(Cl)c(C(N)=O)cnc12
4.7-Dichloro-8-methyl-3-quinolinecarboxamide

Реактанты

Cc1c(N)cccc1Cl
2-methyl-3-chloroaniline
NC(=O)c1cnc2ccc(I)cc2c1Cl
Intermediate 13
NC(=O)c1cnc2ccc(I)cc2c1Cl
4-Chloro-6-iodo-3-quinolinecarboxamide

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Intermediate 68 was prepared from 2-methyl-3-chloroaniline (Aldrich) in a similar manner to Intermediate 13.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07566786B2uspto-grants-2009_07