Реакция #3143

ord-fc482eaeb84f48f6beade7036825e8ec

Растворители

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

The third intermediate, 4,6-dichloro-2-methyl-5-nitropyrimidine is hydrogenated over Raney-Ni as a 10% to 30% solution in toluene to afford the corresponding compound, 4,6-dichloro-2-methyl-5-aminopyrimidine, as a fourth intermediate.

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US05732717uspto-grants-1998_03