Реакция #313131

Уравнение реакции

compound

t-butyl (3S)-3-{[(5-methyl-3-phenyl-4,5-dihydro-5-isoxazolyl)carbonyl]amino}-4-oxo-5-phenoxypentanoate

trifluoroacetic acid

→

title compound

Выход 99.7%

(3S)-3-{[(5-methyl-3-phenyl-4,5-dihydro-5-isoxazolyl)carbonyl]amino}-4-oxo-5-phenoxypentanoic Acid

Выход 99.7%

Растворители

dichloromethane

Условия реакции

Обработка

1. 1
   Концентрированиеconcentrated under reduced pressure

Методика

The compound prepared in Example 3 (530 mg, 1.136 mmol) was dissolved in dichloromethane (6 ml), and trifluoroacetic acid (3 ml) was added at 0□. The mixture was stirred for two hours while it was slowly warmed to room temperature, and concentrated under reduced pressure to give the title compound (Ibb) (465 mg) with a stoichiometric yield.

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