Реакция #310302

Уравнение реакции

indanol

HCl

N2

→

indanyl chloride

Растворители

cyclohexane

Условия реакции

Обработка

1. 1
   workup.ADDITIONis introduced
2. 2
   Другоеto remove the excess of HCl
3. 3
   ДругоеThe reaction mixture is evaporated
4. 4
   workup.DISTILLATIONthe residue is distilled under diminished pressure

Методика

20 g Indanone (obtained according to Example VIII) is added to a solution of 1.5 molequivalent NaAlH2 (OC2H4OCH3)2 in a mixture of benzene and ether in the course of which the temperature raises to 35° C. Then the reaction mixture is stirred during one hour, poured out into ice and extracted with ether. The solution in ether is washed with NaCl solution, dried and evaporated. The residue is distilled under diminished pressure yielding 15.1 g indanol. B.p. 115° C./1 mm Hg. The indanol is dissolved in 100 ml cyclohexane and during 30 min. gaseous HCl is introduced followed by N2 to remove the excess of HCl. The reaction mixture is evaporated and the residue is distilled under diminished pressure yielding 12.9 g indanyl chloride. B.p. 95° C./1 mm Hg.

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