Реакция #3071

Уравнение реакции

3-bromo-4-fluorobenzaldehyde

DMF

triethylamine

MeOH

→

methyl 3-carbomethoxy-4-fluorobenzaldehyde

Условия реакции

Обработка

1. 1
   ЭкстракцияExtraction and chromatography

Методика

A mixture of 1.0 mmol of 3-bromo-4-fluorobenzaldehyde, 4 mL of DMF, 0.2 mL of triethylamine, 0.4 mL of MeOH and 0.05 mmol of Pd(PPh3)4 was heated at 90° C. at 40 psi under CO atmosphere for 16 h. Extraction and chromatography provided methyl 3-carbomethoxy-4-fluorobenzaldehyde.

Источник