Реакция #302882

Уравнение реакции

1,5-Dichloroanthraquinone

3-amino-1-propanol

water

→

1,5-Bis(3-hydroxypropylamino)-anthraquinone

Растворители

DMSO

Условия реакции

Обработка

1. 1
   ТемператураThe mixture is cooled to ˜80°
2. 2
   Другоеhas reached RT
3. 3
   Другоеis isolated by filtration
4. 4
   Промывкаwashed with water (2×50 mL)
5. 5
   Другоеthe un-dissolved product is isolated by filtration
6. 6
   Другоеdried

Методика

1,5-Dichloroanthraquinone (2.8 g; 10 mmol) is mixed with 3-amino-1-propanol (10 mL) in DMSO (50 mL) and heated to 130° C. for 4 hours. The mixture is cooled to ˜80° and added water (150 mL). When the mixture has reached RT the formed precipitate is isolated by filtration, washed with water (2×50 mL), boiled in toluene (200 mL) and the un-dissolved product is isolated by filtration and dried. Yield: 3.2 g (90%).

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