Реакция #3028

Уравнение реакции

hydrochloric acid

2,4-dinitrophenol

octadecyl bromide

sodium carbonate

→

1-octadecyloxy-2,4-dinitrobenzene

Выход 79.1%

Растворители

dimethylformamide

water

Условия реакции

Обработка

1. 1
   Экстракцияextracted with ether
2. 2
   ПромывкаThe extracts were washed with water and brine
3. 3
   Сушкаdried over magnesium sulfate
4. 4
   ДругоеThe solvent was removed
5. 5
   Другоеthe solid recrystallized

Методика

A mixture of 2,4-dinitrophenol (85 wt %, 6.72 g, 31 mmol), octadecyl bromide (20.7 g, 62 mmol), sodium carbonate (6.57 g, 62 mmol) and dimethylformamide (31 mL) was heated to 100° C. under a nitrogen atmosphere for 22 h. The cooled mixture was diluted with water (200 mL), acidified with 10N hydrochloric acid (50 mL) and extracted with ether. The extracts were washed with water and brine, and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give 1-octadecyloxy-2,4-dinitrobenzene (10.7 g, 79%): mp 63.5°-64.0° C.

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