Реакция #3013

Уравнение реакции

2,6-dimethoxy-4-methylaniline

cyclohexanone

water

→

N-cyclohexylidene-2,6-dimethoxy-4-methylaniline

Растворители

toluene

Условия реакции

Обработка

1. 1
   Температураthe reaction mixture is heated
2. 2
   Температураat reflux for 18 hours
3. 3
   Другоеis removed as it
4. 4
   Другоеis formed in the reaction mixture
5. 5
   ДругоеThe toluene is evaporated

Методика

4.2 g of 2,6-dimethoxy-4-methylaniline are dissolved in 50 ml of toluene, 2.45 g of cyclohexanone are then added and the reaction mixture is heated at reflux for 18 hours. The water which is formed is removed as it is formed in the reaction mixture using a Dean and Stark apparatus. The toluene is evaporated and the oily N-cyclohexylidene-2,6-dimethoxy-4-methylaniline residue obtained is used without addition of purification in the following stage.

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