Реакция #2805

Уравнение реакции

1-chloromethyl-2-vinyl-benzene

sodium iodide

water

→

title compound

Выход 95.0%

1-Iodomethyl-2-vinyl-benzene

Выход 95.0%

Растворители

acetone

Условия реакции

Обработка

1. 1
   ТемператураHeat
2. 2
   Температураat gentle reflux for 30 minutes
3. 3
   ТемператураCool
4. 4
   Экстракцияextract with pentane (200 mL)
5. 5
   СушкаDry (MgSO4)
6. 6
   Другоеevaporate the solvent in vacuo

Методика

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give the title compound (95%).

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