Реакция #2499064

Уравнение реакции

(4-bromo-3-fluorophenyl) [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone

1-(4-methoxybenzyl)-4-methylimidazolidin-2-one

3-{4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]-2-fluorophenyl}-1-(4-methoxybenzyl)-4-methylimidazolidin-2-one

→

title compound

1-{4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]-2-fluorophenyl}-5-methylimidazolidin-2-one

Условия реакции

Обработка

1. 1
   Другоеdescribed in Preparation Example 52 and by the reaction and treatment in the same manner as in Example 506

Методика

Using (4-bromo-3-fluorophenyl) [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (157 mg) described in Preparation Example 125 and 1-(4-methoxybenzyl)-4-methylimidazolidin-2-one (106 mg) described in Preparation Example 52 and by the reaction and treatment in the same manner as in Example 506, the title compound (86 mg) was obtained via 3-{4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]-2-fluorophenyl}-1-(4-methoxybenzyl)-4-methylimidazolidin-2-one.

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