Реакция #2467954

Уравнение реакции

(2S,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate

(2R,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate

→

Methyl-2-benzamidomethyl-3-oxobutyrate

Условия реакции

Обработка

1. 1
   workup.ADDITIONSimilarly, an ADH-LK variant with SEQ ID No.94 containing 10 mutations
2. 2
   Другоеgave primarily the (2R,3R) stereoisomer

Методика

The ADH-LK variant with SEQ ID No. 90 was used for further evolution of an efficient KRED for production of (2S,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate. Similarly, an ADH-LK variant with SEQ ID No.94 containing 10 mutations compared to ADH-LK which gave primarily the (2R,3R) stereoisomer, was used for further evolution of an efficient KRED for production of (2R,3R)-methyl-2-benzamidomethyl-3-hydroxybutyrate.

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