Реакция #2460284

Уравнение реакции

4-Bromophenol

potassium carbonate

benzyl bromide

→

4-benzyloxybromobenzene

Растворители

water

acetone

ethyl acetate

Условия реакции

Обработка

1. 1
   ТемператураThe reaction was refluxed under nitrogen
2. 2
   ТемператураAfter 5-6 hours of reflux
3. 3
   Другоеthe organic layer was separated
4. 4
   Сушкаdried over magnesium sulfate
5. 5
   Другоеevaporated to dryness
6. 6
   Другоеto afford a white fluffy powder

Методика

4-Bromophenol (2 g, 0.0116 mol) in acetone (40 ml) was treated with potassium carbonate (1.91 g, 1.2 equivalents) and benzyl bromide (1.44 ml, 1.05 equivalents). The reaction was refluxed under nitrogen. After 5-6 hours of reflux, the reaction was cooled to room temperature and diluted with an equal volume of ethyl acetate. This was diluted further with water and the organic layer was separated, dried over magnesium sulfate and evaporated to dryness to afford a white fluffy powder. Yield=2.36 g (73%).

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