Реакция #2375569

Уравнение реакции

N-(4-cyanophenyl)-glycine

3-amino-4-methylamino-benzoic acid-N-(2-pyridyl)-N-ethoxycarbonylmethyl-amide

→

1-Methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-ethoxycarbonylmethyl-amide

Выход 24.0%

Растворители

dichloromethane methanol

Условия реакции

Методика

Prepared analogously to Example 25c from N-(4-cyanophenyl)-glycine and 3-amino-4-methylamino-benzoic acid-N-(2-pyridyl)-N-ethoxycarbonylmethyl-amide. Yield: 24% of theory, Rf value: 0.56 (silica gel; dichloromethane/methanol=4:1)

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