Реакция #2358520

Уравнение реакции

1-(2-bromoethoxy)-3-chloro-5-methylsulfonyl-benzene

isobutylamine

( 2 )

N-{2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl}-N-propylamine

→

N-{2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl}-N-isobutylamine

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ДругоеPreparation

Методика

Preparation according to Example 1 but performed in one portion: 1-(2-bromoethoxy)-3-chloro-5-methylsulfonyl-benzene (0.05 g, 0.16 mmol) and isobutylamine (0.2 ml, 1.3 mmol) in ethanol (5 ml). MS m/z (relative intensity, 70 eV) 289 (M+, 1), 246 (bp), 138 (2), 86 (70), 56 (17).

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