Реакция #2306

Уравнение реакции

Oxalyl chloride

4-((4-pyridyl)piperazin-1-yl)benzoic acid

→

4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride

Растворители

dichloromethane

Условия реакции

Обработка

1. 1
   Другоеevaporated to dryness

Методика

Oxalyl chloride (0.5 ml) was added to a stirred suspension of 4-((4-pyridyl)piperazin-1-yl)benzoic acid in dichloromethane (15 ml), followed by DMF (1 drop). The mixture was stirred for 2 hours and evaporated to dryness to give 4-[(4-pyridyl)piperazin-1-yl]benzoyl chloride which was used immediately.

Источник