Реакция #2275752

Уравнение реакции

N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide

2-(4-oxo-cyclohexyl)-isoindole-1,3-dione

→

title compounds

N-({1-[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Условия реакции

Методика

The title compounds were prepared as white solids from the reductive amination of 2-(4-oxo-cyclohexyl)-isoindole-1,3-dione (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in Example 2 Step C) using the procedure described in Step D of Example 1.

Источник