Реакция #2275746

Уравнение реакции

N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide

3-methyl-1-(4-oxo-cyclohexyl)-1H-pyridin-2-one

→

title compounds

N-({1-[4-(3-Methyl-2-oxo-2H-pyridin-1-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Условия реакции

Методика

The title compounds were prepared as white solids from the reductive amination of 3-methyl-1-(4-oxo-cyclohexyl)-1H-pyridin-2-one (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in Example 2 Step C) using the procedure described in Step D of Example 1.

Источник