Реакция #220382

ord-73e6d22957d44f7c958ce0e5a807c3e5

Уравнение реакции

Nc1cc(F)cc(F)c1
3,5-difluoroaniline
CC(Cl)C(=O)O
2-chloropropionic acid
→
C[C@H](Nc1cc(F)cc(F)c1)C(=O)O
N-(3,5-difluorophenyl)alanine

Реактанты

Nc1cc(F)cc(F)c1
3,5-difluoroaniline
CC(Cl)C(=O)O
2-chloropropionic acid

Реагенты

Нет

Условия реакции

Подробные условия
See reaction.notes.procedure_details.

Методика

Using the procedure set forth in U.S. Pat. No. 3,598,859 and Example Q above, N-(3,5-difluorophenyl)alanine was prepared using 3,5-difluoroaniline (Aldrich) and 2-chloropropionic acid (Aldrich).

Источник

DOI: 10.6084/m9.figshare.5104873.v1Патент: US07390801B2uspto-grants-2008_06