Реакция #2196656

Уравнение реакции

(S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one

2-bromo-5-phenyl-1,3,4-thiadiazole

→

title compound

(R)-3′-(5-Phenyl-1,3,4-thiadiazol-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one

Условия реакции

Обработка

1. 1
   ДругоеThe compound was prepared by a method analogous to

Методика

The compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 2-bromo-5-phenyl-1,3,4-thiadiazole using 5 equivalents of copper (I) iodide. The title compound (180 mg) was obtained as a yellow solid, m/z 343 (MH+).

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