Реакция #2195498

Уравнение реакции

product

Diethyl 3,3-difluoropentanedioate

benzylamine

→

title compound

1-Benzyl-4,4-difluoropiperidine-2,6-dione

Условия реакции

Обработка

1. 1
   Другоеpurify by silica gel chromatography

Методика

React an 8.1 mmol portion of the product of Example 14 with benzylamine using the general procedure set forth in Example 8, and purify by silica gel chromatography using ethyl acetate/hexane as eluant to yield the title compound.

Источник