Реакция #2195488

Уравнение реакции

hydrochloric acid

Triethylamine

sodium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate

dichloromethane

→

trimethylammonium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate

Выход 75.0%

Растворители

water

Условия реакции

Обработка

1. 1
   workup.ADDITIONwere added, whereupon the mixture
2. 2
   ДругоеThe organic layer was separated
3. 3
   Промывкаwashed with water
4. 4
   ПромывкаFrom the organic layer as washed
5. 5
   workup.DISTILLATIONthe dichloromethane was distilled off in vacuum
6. 6
   workup.ADDITIONDiethyl ether was added to the residue for recrystallization
7. 7
   ФильтрацияThe crystals were filtered
8. 8
   Другоеdried
9. 9
   Другоеobtaining the target compound in a yield of 75%

Методика

Triethylamine was dissolved in cold water. To the solution, hydrochloric acid was added, and sodium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate prepared in Synthesis Example 27 and dichloromethane were added, whereupon the mixture was stirred. The organic layer was separated and washed with water. From the organic layer as washed, the dichloromethane was distilled off in vacuum. Diethyl ether was added to the residue for recrystallization. The crystals were filtered and dried, obtaining the target compound in a yield of 75%.

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