Реакция #2195486

Уравнение реакции

Toluene

1,1,3,3,3-pentafluoropropen-2-yl benzoate

sodium hydrogen sulfite

benzoyl peroxide

→

sodium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate

Выход 43.0%

Растворители

water

Условия реакции

Обработка

1. 1
   Другоеat 85° C.
2. 2
   Другоеfor 65 hours
3. 3
   Температураto cool
4. 4
   Другоеto separate a water layer
5. 5
   workup.ADDITIONA saturated sodium chloride aqueous solution was added to the water layer whereupon white crystals
6. 6
   ФильтрацияThe crystals were collected by filtration
7. 7
   Промывкаwashed with a small volume of saturated sodium chloride aqueous solution
8. 8
   Другоеdried in vacuum

Методика

10.0 g of 1,1,3,3,3-pentafluoropropen-2-yl benzoate, which had been synthesized by a conventional technique, was dispersed in 72 g of water, after which 12.0 g of sodium hydrogen sulfite and 1.24 g of benzoyl peroxide were added. The reaction took place at 85° C. for 65 hours. The reaction solution was allowed to cool. Toluene was added, followed by separatory operation to separate a water layer. A saturated sodium chloride aqueous solution was added to the water layer whereupon white crystals settled out. The crystals were collected by filtration, washed with a small volume of saturated sodium chloride aqueous solution and then dried in vacuum, obtaining the target compound, sodium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate. White crystals, 5.85 g (yield 43%).

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