Реакция #2191

Уравнение реакции

N-(4-chloro-4'-trifluoromethylsulfonylmethylbenzhydryl) -N'-methoxycarbonylhydrazine

hydrochloric acid

→

desired product

N-(4-Chloro-4'-trifluoromethylsulfonylmethylbenzhydryl)-N'-methoxycarbonylhydrazine Hydrochloride

Растворители

methanol

Условия реакции

Обработка

1. 1
   workup.ADDITIONwas added
2. 2
   ТемператураThe mixture was gradually heated to the reflux temperature
3. 3
   workup.STIRRINGstirred for 2 hours
4. 4
   Температураunder reflux
5. 5
   workup.WAITit was left
6. 6
   Температураto cool
7. 7
   workup.DISTILLATIONThe solvent was distilled off under reduced pressure

Методика

N-(4-chloro-4'-trifluoromethylsulfonylmethylbenzhydryl) -N'-methoxycarbonylhydrazine (1.6 g) was added to methanol (80 ml), and hydrochloric acid (3 ml) was added thereto with stirring at room temperature. The mixture was gradually heated to the reflux temperature and stirred for 2 hours under reflux, and then it was left to cool. The solvent was distilled off under reduced pressure to obtain the desired product as a slightly yellow powder (1.6 g, melting point: 52° to 54° C., yield: 91.5%).

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