Реакция #218693

Уравнение реакции

2-isopropyl-4,9-dihydro-3-thia-1,4,9-triazabenzo[f]azulene-10-thione

2(S)-(2(S)-methoxypropyl)piperazine

2(S)-(2(R)-methoxypropyl)piperazine

→

title compound

10-[3(S)-(2(R)-Methoxy-propyl)-piperazin-1-yl]-2-isopropyl-4H-3-thia-1,4,9-triazabenzo[f]azulene

Условия реакции

Методика

In a manner similar to that described in Example 359, combine 2-isopropyl-4,9-dihydro-3-thia-1,4,9-triazabenzo[f]azulene-10-thione (0.865 g, 3.14 mmol) and the isomer mixture of 2(S)-(2(S)-methoxypropyl)piperazine and 2(S)-(2(R)-methoxypropyl)piperazine (0.497 g, 3.14 mmol) to obtain the title compound as a mixture of isomers: mass spectrum (APCI): m/z 400.2 (M+1).

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