Реакция #2186175

Уравнение реакции

benzoyl chloride

sorbitol

→

Sorbitol Hexabenzoate

Выход 74.0%

Растворители

triethylamine

Условия реакции

Обработка

1. 1
   workup.STIRRINGthe resulting mixture was stirred for an additional 30 minutes
2. 2
   ДругоеAfter completion of the reaction
3. 3
   Другоеwas lowered to room temperature
4. 4
   Другоеthe resulting precipitates
5. 5
   Фильтрацияwere collected by filtration
6. 6
   ПромывкаThereafter, washing
7. 7
   workup.ADDITIONby adding ethyl acetate-pure water
8. 8
   ДругоеSubsequently, the organic phase was collected
9. 9
   workup.DISTILLATIONethyl acetate was distilled out under vacuum, whereby 100 parts by weight (at a yield of 74 percent) of white crystals
10. 10
    Другоеwere obtained

Методика

While stirring, 71 parts by weight of benzoyl chloride were dripped over 30 minutes into a mixed solution of 30 parts by weight of sorbitol and 101 parts by weight of triethylamine maintained at 100° C., and the resulting mixture was stirred for an additional 30 minutes. After completion of the reaction, the temperature was lowered to room temperature, and the resulting precipitates were collected by filtration. Thereafter, washing was performed by adding ethyl acetate-pure water. Subsequently, the organic phase was collected and ethyl acetate was distilled out under vacuum, whereby 100 parts by weight (at a yield of 74 percent) of white crystals were obtained. The molecular weight of the resulting compound was 809.

Источник