Реакция #2161223

Уравнение реакции

porphyrin

pyrrole

4-trimethylsilylethynylbenzaldehyde

methanol

→

porphyrin

Выход 12.0%

tetrakis(4-trimethylsilylethynylphenyl)porphyrin

Выход 12.0%

Растворители

propionic acid

Условия реакции

Обработка

1. 1
   ТемператураThe temperature was subsequently increased
2. 2
   Температураat reflux for 4 hours
3. 3
   workup.WAITwas then left
4. 4
   Другоеto crystallize
5. 5
   ФильтрацияThe medium was filtered over sintered glass
6. 6
   Промывкаthe product was rinsed with methanol

Методика

5.02 g of 4-trimethylsilylethynylbenzaldehyde (25 mmol) were dissolved in 210 ml of propionic acid and then heated to 80° C. 1.72 ml of pyrrole (25 mmol) were subsequently added portionwise over a period of one hour. The temperature was subsequently increased and the mixture was kept at reflux for 4 hours. After a return to ambient temperature, 75 ml of methanol were added to the reaction medium, which was then left to stand for 14 hours in order for the porphyrin to crystallize. The medium was filtered over sintered glass and the product was rinsed with methanol. 2.87 g (3 mmol; yield 12%) of the expected porphyrin (1) were obtained in the form of a purple powder.

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