Реакция #216076

Уравнение реакции

Octadecylamine

Glycidol

→

white solid

Выход 95.9%

3-Octadecylamino-1,2-Dihydroxy-Propane

Выход 95.9%

Растворители

methanol

Условия реакции

Обработка

1. 1
   Температураunder reflux for one additional hour
2. 2
   Температураcooled to room temperature
3. 3
   Другоеevaporated to dryness

Методика

Octadecylamine (18 g) was dissolved in 200 ml methanol and heated to 60° C. Glycidol (4.95 g) was added dropwise under constant stirring over one and half hours. The reaction mixture was kept under reflux for one additional hour, and then cooled to room temperature, and evaporated to dryness, resulting in 22 g white solid material. This was then recrystallized from hexane, to yield ODP, mp 81°-83° C.

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