Реакция #215143

Уравнение реакции

water

3-sulfamoyl-4-chlorobenzoyl chloride

1-cyclohexyl-1-phenyl hydrazine

sodium bicarbonate

→

1-Cyclohexyl-1-phenyl-2-(3-sulfamoyl-4-chlorobenzoyl)-hydrazine

Растворители

isopropanol

Условия реакции

Обработка

1. 1
   Температураchilled
2. 2
   workup.STIRRINGThe mixture was stirred for 2 hours at room temperature and for 2.5 hours at 40°-50° C
3. 3
   Другоеwas recrystallized from aqueous ethanol

Методика

A mixture of 8.5 g (0.045 mol) 1-cyclohexyl-1-phenyl hydrazine in 50 ml isopropanol and 4.7 g (0.045 mol) sodium bicarbonate was stirred and chilled. Addition of 11.36 g (0.045 mol) 3-sulfamoyl-4-chlorobenzoyl chloride was made in several portions. The mixture was stirred for 2 hours at room temperature and for 2.5 hours at 40°-50° C. Dilution of the reaction mixture with water yielded a solid material which was recrystallized from aqueous ethanol. M.P. 216°-217° C.

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