Реакция #214754

Уравнение реакции

N-(2-chloro-6-nitrobenzyl)-L-alanine ethyl ester

→

N-(2-amino-6-chlorobenzyl)-L-alanine ethyl ester

Выход 99.0%

Растворители

ethanol

Условия реакции

Обработка

1. 1
   ФильтрацияAfter completion of the hydrogenation, the catalyst was filtered off
2. 2
   Другоеthe filtrate was evaporated to dryness

Методика

A solution of 14.3 g of N-(2-chloro-6-nitrobenzyl)-L-alanine ethyl ester in 50 ml of absolute ethanol was hydrogenated in the presence of 1 g of Raney nickel. After completion of the hydrogenation, the catalyst was filtered off and the filtrate was evaporated to dryness. There were obtained 12.6 g (99% of theory) of N-(2-amino-6-chlorobenzyl)-L-alanine ethyl ester; nD22 =1.5430.

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