Реакция #2144141

Уравнение реакции

4-chloro-3-nitro-quinoline

isobutyl amine

triethanolamine

→

4-isobutyl-3-nitro quinoline

Растворители

toluene

Условия реакции

Обработка

1. 1
   ПромывкаAfer washing
2. 2
   Другоеphase separation

Методика

4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethanolamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. Afer washing and phase separation, the organic solution is ready for the next step.

Источник